ABSTRACT
Primary squamous cell carcinoma of the endometrium is very rare. In 1928 Flumann suggested three criteria for diagnosis: (1) no coexisting endometrial adenocarcinoma, (2) no connection between the endometrial squamous cell carcinoma and squamous epithelium of the cervix, and (3) no cervical squamous cell carcinoma. In 1975, the World Health Organization (WHO) updated Flumann's criteria by adding that the tumor must contain clear evidence of squamous differentiation, such as the presence of intercellular bridges and/or keratin. Most patients with endometrial squmamous cell carcinoma have had poor prognosis regardless of their stages of disease or treatment. In this report we present the clinical and pathological findings of a case of a primary squamous cell carcinoma that developed in the endometrial cavity of a 65-year-old patient with a review of the concerned literatures.
Subject(s)
Aged , Female , Humans , Adenocarcinoma , Carcinoma, Squamous Cell , Cervix Uteri , Diagnosis , Endometrium , Epithelium , Prognosis , World Health OrganizationABSTRACT
Struma Ovarii is a teratoma with thyroid tissue as the predominant (>50%) constituent. It is rare, representing about 2% of all teratomas, and its malignant transformation, less than 5% of struma ovarii. Presenting symptoms are not specific, therefore pre-operative diagnosis of malignant struma ovarii is difficult and most diagnosis of malignant struma ovaii is determined by post-operative histologic findings. Because of the rarity of malignant struma ovarii, there is considerable confusion concerning diagnosis and management. A postmenopausal woman presented with pelvic mass and lower abdominal pain and explo-laparotomy was performed. Then, pathologic report was identified as malignant struma ovarii. We report a case of malignant struma ovarii with brief review of literature